I've been reading through the introductory info etc. I dont know... I dont think this is before WoD. I get the feeling that it is definately Post-WoD. I remember reading in one of White Wolfs Prophecy books that the world would be saved by the woman with the mark of the Crecent Moon on her. Sounds like the Empress. Also the Contagion and the barriers getting broken down sounds a lot like the gauntlet falling and the end of the world. I dont know.
I think this could be a hell of a setting, though. You could pull from all sorts of different cultures, mix them as you see fit, and create your own world.